Journal
CHEMICAL SOCIETY REVIEWS
Volume 32, Issue 6, Pages 327-337Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b211643j
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The mammalian cell surface is a highly heterogeneous chemical environment with proteins, carbohydrates, lipids and composite molecules controlling vital cell functions. Chemical modification of this environment is a challenge due to the complexity of the surface chemistry and the fragility of the cell. Here, we review recent attempts to perform targeted, non-genetically controlled, changes to cell surface chemistry. Potential applications of cell surface engineering are presented.
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