Oligosaccharide synthesis using fluorous-tag method

The fluorous-tag method is a methodology which could purify product by partitioning the product mixture between a fluorous solvent such as perfluorohexane and an organic solvent, and is an excellent strategic alternative to solid-phase synthesis. In this report, the fluorous-tag method is initially described. The possibility of oligosaccharide synthesis using fluorous-tag method is then discussed.