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Native Microbiota Shape Insect Vector Competence for Human Pathogens

Journal

CELL HOST & MICROBE
Volume 10, Issue 4, Pages 307-310

Publisher

CELL PRESS
DOI: 10.1016/j.chom.2011.09.006

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Funding

  1. National Institutes of Health (NIH)/National Institute of Allergy and Infectious Diseases (NIAID) [1F31AI080161-01A1, 1R01AI061576, R01AI081877]
  2. American Society for Microbiology
  3. Calvin A. and Helen H. Lang fellowship

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The resident microbiota of insect vectors can impede transmission of human pathogens. Recent studies have highlighted the capacity of endogenous bacteria to decrease viral and parasitic infections in mosquito and tsetse fly vectors by activating their immune responses or directly inhibiting pathogen development. These microbes may prove effective agents for manipulating the vector competence of malaria and other important human pathogens.

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