Journal
CELL HOST & MICROBE
Volume 6, Issue 3, Pages 201-203Publisher
CELL PRESS
DOI: 10.1016/j.chom.2009.08.008
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Recent discoveries have revealed the importance of the vitamin D-dependent generation of antimicrobial peptides in human host defense against Mycobacterium tuberculosis. Now, Yuk et al. (2009) show how vitamin D induces autophagy and mediates colocalization of Mycobacterium tuberculosis and antimicrobial peptides within an autophagolysosome, leading to killing of the bacterium.
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