Journal
CELL HOST & MICROBE
Volume 4, Issue 4, Pages 308-310Publisher
CELL PRESS
DOI: 10.1016/j.chom.2008.09.003
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The fungal pathogen Cryptococcus neoformans has three major virulence factors: growth at 37 degrees C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al. (2008) employed signature tagged mutagenesis to systematically identify virulence genes. Remarkably, mutations in many of these genes did not influence the major virulence traits.
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