Journal
CELL HOST & MICROBE
Volume 3, Issue 2, Pages 59-61Publisher
CELL PRESS
DOI: 10.1016/j.chom.2008.01.005
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Host responses to cytomegalovirus infection include initial early production of alpha and beta interferons, also called type I interferons, which are elicited directly by viral products via Toll-like receptors. New data indicate that, preceding these events, an earlier critical type I interferon elicited in primary infected stromal cells via the lymphotoxin beta receptor system and mediated by B cells is necessary to kick-start an efficient antiviral response.
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