Related references
Note: Only part of the references are listed.Human and mouse granzyme M display divergent and species-specific substrate specificities
Stefanie A. H. de Poot et al.
BIOCHEMICAL JOURNAL (2011)
Mouse granzyme K has pro-inflammatory potential
L. T. Joeckel et al.
CELL DEATH AND DIFFERENTIATION (2011)
The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5′-diphosphate-ribose) polymerase-1
Pengcheng Zhu et al.
BLOOD (2009)
Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity
V. Romero et al.
CELL DEATH AND DIFFERENTIATION (2009)
Granzyme F induces a novel death pathway characterized by Bid-independent cytochrome c release without caspase activation
L. Shi et al.
CELL DEATH AND DIFFERENTIATION (2009)
Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement
Monica D. Prakash et al.
IMMUNOLOGY AND CELL BIOLOGY (2009)
Nucleophosmin Is Cleaved and Inactivated by the Cytotoxic Granule Protease Granzyme M during Natural Killer Cell-mediated Killing
Sean P. Cullen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Ignition of p53 Bomb Sensitizes Tumor Cells to Granzyme K-Mediated Cytolysis
Guoqiang Hua et al.
JOURNAL OF IMMUNOLOGY (2009)
Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma
Wendy Anne Boivin et al.
LABORATORY INVESTIGATION (2009)
Death by a thousand cuts: Granzyme pathways of programmed cell death
Dipanjan Chowdhury et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions
Brice Korkmaz et al.
BIOCHIMIE (2008)
Granzyme A cleaves a mitochondrial complex I protein to initiate caspase-independent cell death
Denis Martinvalet et al.
CELL (2008)
Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response
Sunil S. Metkar et al.
IMMUNITY (2008)
Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor
Marguerite S. Buzza et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
NK cell protease granzyme M targets α-tubulin and disorganizes the microtubule network
Niels Bovenschen et al.
JOURNAL OF IMMUNOLOGY (2008)
Granzyme H induces apoptosis of target tumor cells characterized by DNA fragmentation and Bid-dependent mitochondrial damage
Qiang Hou et al.
MOLECULAR IMMUNOLOGY (2008)
Mechanisms of granule-dependent killing
S. P. Cullen et al.
CELL DEATH AND DIFFERENTIATION (2008)
Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin
J. Pardo et al.
CELL DEATH AND DIFFERENTIATION (2007)
Antiangiogenic plasma activity in patients with systemic sclerosis
Mary Jo Mulligan-Kehoe et al.
ARTHRITIS AND RHEUMATISM (2007)
Natural killer cell-derived human granzyme H induces an alternative, caspase-independent cell-death program
Edward Fellows et al.
BLOOD (2007)
Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis
Guoqiang Hua et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs
Todd A. Fehniger et al.
IMMUNITY (2007)
Granzyme K directly processes bid to release cytochrome c and endonuclease g leading to mitochondria-dependent cell death
Tongbiao Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition
Felipe Andrade et al.
EMBO JOURNAL (2007)
Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells
T. Zhao et al.
CELL DEATH AND DIFFERENTIATION (2007)
Human and murine granzyme B exhibit divergent substrate preferences
Sean P. Cullen et al.
JOURNAL OF CELL BIOLOGY (2007)
Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma
Cornelia M. Tschopp et al.
BLOOD (2006)
Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis
Carly R. K. Loeb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Granzyme M directly cleaves inhibitor of caspase-activated DNase (CAD) to unleash CAD leading to DNA fragmentation
Hongxia Lu et al.
JOURNAL OF IMMUNOLOGY (2006)
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death
Dipanjan Chowdhury et al.
MOLECULAR CELL (2006)
p53 is cleaved by caspases generating fragments localizing to mitochondria
BS Sayan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70
PC Zhu et al.
EMBO REPORTS (2006)
Identification of α-tubulin as a granzyme B substrate during CTL-mediated apoptosis
IS Goping et al.
JOURNAL OF CELL SCIENCE (2006)
Functional analysis of granzyme M and its role in immunity to infection
LI Pao et al.
JOURNAL OF IMMUNOLOGY (2005)
Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin
MS Buzza et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis
D Martinvalet et al.
IMMUNITY (2005)
Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions
PA Revell et al.
JOURNAL OF IMMUNOLOGY (2005)
Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B
C Adrain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner
M Sebbagh et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
CTL secretory lysosomes: biogenesis and secretion of a harmful organelle
G Bossi et al.
SEMINARS IN IMMUNOLOGY (2005)
Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates
BJ Rukamp et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B
S Mahrus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis
J Pardo et al.
JOURNAL OF CELL BIOLOGY (2004)
Granzymes and caspase 3 play important roles in control of gammaherpesvirus latency
J Loh et al.
JOURNAL OF VIROLOGY (2004)
Granzyme M mediates a novel form of perforin-dependent cell death
JM Kelly et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cutting edge: Granzymes A and B are not essential for perforin-mediated tumor rejection
MJ Smyth et al.
JOURNAL OF IMMUNOLOGY (2003)
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
ZS Fan et al.
CELL (2003)
Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors
VR Sutton et al.
IMMUNITY (2003)
Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition
IS Goping et al.
IMMUNITY (2003)
Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A
ZS Fan et al.
NATURE IMMUNOLOGY (2003)
Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway
U Muller et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A
ZS Fan et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK
DA Thomas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction
CE Hirst et al.
MOLECULAR HUMAN REPRODUCTION (2001)
Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation
E Sharif-Askari et al.
EMBO JOURNAL (2001)
Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis
D Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway
MJ Pinkoski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Induction of rapid histone degradation by the cytotoxic T lymphocyte protease granzyme A
D Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cutting edge: Granzyme B proteolysis of a neuronal glutamate receptor generates an autoantigen and is modulated by glycosylation
LC Gahring et al.
JOURNAL OF IMMUNOLOGY (2001)
Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members Bid and Bax
JA Heibein et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Initiation of apoptosis by granzyme B requires direct cleavage of Bid, but not direct granzyme B-mediated caspase activation
VR Sutton et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis
DA Thomas et al.
IMMUNITY (2000)
Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving bid
M Barry et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors
CM Kam et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY (2000)
Granzyme A, a noncytolytic component of CD8(+) cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice
RA Pereira et al.
JOURNAL OF VIROLOGY (2000)