Journal
CELL DEATH AND DIFFERENTIATION
Volume 19, Issue 1, Pages 28-35Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/cdd.2011.153
Keywords
granzymes; apoptosis; cytotoxic T cells; NK cells
Categories
Funding
- Canadian Institutes of Health Research
- Canadian Cancer Society
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Granzymes (Grs) were discovered just over a quarter century ago. They are produced by cytotoxic T cells and natural killer cells and are released upon interaction with target cells. Intensive biochemical, genetic, and biological studies have been performed in order to study their roles in immunity and inflammation. This review summarizes research on the family of Grs. Cell Death and Differentiation (2012) 19, 28-35; doi:10.1038/cdd.2011.153; published online 4 November 2011
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