Related references
Note: Only part of the references are listed.MicroRNA-339 and microRNA-556 regulate Klotho expression in vitro
Stephen J. Mehi et al.
AGE (2014)
Senescence-associated lncRNAs: senescence-associated long noncoding RNAs
Kotb Abdelmohsen et al.
AGING CELL (2013)
A Genetic Program Promotes C. elegans Longevity at Cold Temperatures via a Thermosensitive TRP Channel
Rui Xiao et al.
CELL (2013)
Rejuvenation of Gene Expression Pattern of Aged Human Skin by Broadband Light Treatment: A Pilot Study
Anne Lynn S. Chang et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2013)
MicroRNA-34a regulates cardiac ageing and function
Reinier A. Boon et al.
NATURE (2013)
Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a chi
Carolin Cornelius et al.
IMMUNITY & AGEING (2013)
Circulating inflamma-miRs in aging and age-related diseases
Fabiola Olivieri et al.
Frontiers in Genetics (2013)
Gadd45 proteins: Relevance to aging, longevity and age-related pathologies
Alexey A. Moskalev et al.
AGEING RESEARCH REVIEWS (2012)
VDAC isoforms in mammals
Angela Messina et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
The role of D-GADD45 in oxidative, thermal and genotoxic stress resistance
Alexey Moskalev et al.
CELL CYCLE (2012)
The Critical Role of Metabolic Pathways in Aging
Nir Barzilai et al.
DIABETES (2012)
Cancer cell senescence: a new frontier in drug development
Claire J. Cairney et al.
DRUG DISCOVERY TODAY (2012)
Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases
Alex Zhavoronkov et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2012)
The sirtuin SIRT6 regulates lifespan in male mice
Yariv Kanfi et al.
NATURE (2012)
Age-related changes in gene expression in tissues of the sea urchin Strongylocentrotus purpuratus
Jeannette Loram et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2012)
Postnatal development- and age-related changes in DNA-methylation patterns in the human genome
Paraskevi Salpea et al.
NUCLEIC ACIDS RESEARCH (2012)
Overexpression of Fatty-Acid-beta-Oxidation-Related Genes Extends the Lifespan of Drosophila melanogaster
Shin-Hae Lee et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Therapies in inborn errors of oxidative metabolism
Manuel Schiff et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)
Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population
Jordana T. Bell et al.
PLOS GENETICS (2012)
The endoplasmic reticulum stress response in aging and age-related diseases
Marishka K. Brown et al.
FRONTIERS IN PHYSIOLOGY (2012)
Increase of Drosophila melanogaster lifespan due to D-GADD45 overexpression in the nervous system
E. N. Plyusnina et al.
BIOGERONTOLOGY (2011)
Radiation hormesis and radioadaptive response in Drosophila melanogaster flies with different genetic backgrounds: the role of cellular stress-resistance mechanisms
A. A. Moskalev et al.
BIOGERONTOLOGY (2011)
A Muscle-Specific p38 MAPK/Mef2/MnSOD Pathway Regulates Stress, Motor Function, and Life Span in Drosophila
Alysia Vrailas-Mortimer et al.
DEVELOPMENTAL CELL (2011)
Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic Mice
Masaki Naito et al.
DIABETES (2011)
Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage
Filipe Cabreiro et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Methods for Structuring Scientific Knowledge from Many Areas Related to Aging Research
Alex Zhavoronkov et al.
PLOS ONE (2011)
The Histone Demethylase Jarid1b (Kdm5b) Is a Novel Component of the Rb Pathway and Associates with E2f-Target Genes in MEFs during Senescence
Jeroen H. Nijwening et al.
PLOS ONE (2011)
Physiological roles revealed by ghrelin and ghrelin receptor deficient mice
Rosie G. Albarran-Zeckler et al.
PEPTIDES (2011)
The new science of ageing Introduction
Linda Partridge et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)
The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO
Gizem Rizki et al.
PLOS GENETICS (2011)
Roles of GSK3 in metabolic shift toward abnormal anabolism in cell senescence
You-Mie Kim et al.
MITOCHONDRIAL RESEARCH IN TRANSLATIONAL MEDICINE (2010)
Aging and exercise affect the level of protein acetylation and SIRT1 activity in cerebellum of male rats
Orsolya Marton et al.
BIOGERONTOLOGY (2010)
Apolipoprotein D An overview of its role in aging and age-related diseases
Julien Muffat et al.
CELL CYCLE (2010)
Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3
Ji-Won Jung et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Correlation of plasma resistin with obesity and insulin resistance in type 2 diabetic patients
M. Y. Gharibeh et al.
DIABETES & METABOLISM (2010)
Apolipoprotein E and its role in aging and survival
Francesca Bonomini et al.
EXPERIMENTAL GERONTOLOGY (2010)
Molecular mechanisms of proteasome plasticity in aging
Karl A. Rodriguez et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2010)
The new biology of ageing
Linda Partridge
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2010)
Extending Healthy Life Span-From Yeast to Humans
Luigi Fontana et al.
SCIENCE (2010)
Insulin/IGF-I and Related Signaling Pathways Regulate Aging in Nondividing Cells: from Yeast to the Mammalian Brain
Edoardo Parrella et al.
THESCIENTIFICWORLDJOURNAL (2010)
AMP-activated Protein Kinase and FoxO Transcription Factors in Dietary Restriction-induced Longevity
Eric L. Greer et al.
INTERNATIONAL SYMPOSIUM ON OLFACTION AND TASTE (2009)
Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity in Drosophila
Svetlana N. Radyuk et al.
BIOCHEMICAL JOURNAL (2009)
Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging
Dao-Fu Dai et al.
CIRCULATION (2009)
Converging Pathways in Lifespan Regulation
Sri Devi Narasimhan et al.
CURRENT BIOLOGY (2009)
RAS in cellular transformation and senescence
Gina M. DeNicola et al.
EUROPEAN JOURNAL OF CANCER (2009)
The signaling hubs at the crossroad of longevity and age-related disease networks
Marina Wolfson et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
JNK/FOXO-mediated Neuronal Expression of Fly Homologue of Peroxiredoxin II Reduces Oxidative Stress and Extends Life Span
Kyu-Sun Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Genetic Evidence Linking Age-Dependent Attenuation of the 26S Proteasome with the Aging Process
Ayako Tonoki et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Increasing organismal healthspan by enhancing mitochondrial protein quality control
Karin Luce et al.
NATURE CELL BIOLOGY (2009)
Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
Colin Selman et al.
SCIENCE (2009)
Hsps and aging
John Tower
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Positive Feedback between Transcriptional and Kinase Suppression in Nematodes with Extraordinary Longevity and Stress Resistance
Cagdap Tazearslan et al.
PLOS GENETICS (2009)
Pparγ2 Is a Key Driver of Longevity in the Mouse
Carmen Argmann et al.
PLOS GENETICS (2009)
Remarkable longevity and stress resistance of nematode PI3K-null mutants
Srinivas Ayyadevara et al.
AGING CELL (2008)
Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity
Camille C. Caldeira da Silva et al.
AGING CELL (2008)
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
Anne Simonsen et al.
AUTOPHAGY (2008)
Born to run;: the story of the PEPCK-Cmus mouse
Richard W. Hanson et al.
BIOCHIMIE (2008)
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans
Jennifer M. A. Tullet et al.
CELL (2008)
Stress-response hormesis and aging: That which Does Not Kill Us Makes Us Stronger
David Gems et al.
CELL METABOLISM (2008)
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
Colin Selman et al.
FASEB JOURNAL (2008)
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
Jerome Lapointe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Evolution of ageing since Darwin
Michael R. Rose et al.
JOURNAL OF GENETICS (2008)
Adiponectin levels and genotype: A potential regulator of life span in humans
Gil Atzmon et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)
A role for autophagy in the extension of lifespan by dietary restriction in C-elegans
Malene Hansen et al.
PLOS GENETICS (2008)
Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila
Julien Muffat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Functionally significant insulin-like growth factor I receptor mutations in centenarians
Yousin Suh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Autophagy and aging: keeping that old broom working
Ana Maria Cuervo
TRENDS IN GENETICS (2008)
It's Not How Fat You Are, It's What You Do with It That Counts.
Samuel Virtue et al.
PLOS BIOLOGY (2008)
Radiation-induced life span alteration of Drosophila lines with genotype differences
Alexey Moskalev
BIOGERONTOLOGY (2007)
Brca1 heterozygous mice have shortened life span and are prone to ovarian tumorigenesis with haploinsufficiency upon ionizing irradiation
Y-M Jeng et al.
ONCOGENE (2007)
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
Andrew S. Brack et al.
SCIENCE (2007)
Brain IRS2 signaling coordinates life span and nutrient homeostasis
Akiko Taguchi et al.
SCIENCE (2007)
Delayed ageing through damage protection by the Arf/p53 pathway
Ander Matheu et al.
NATURE (2007)
PHA-4/Foxa mediates diet-restriction-induced longevity of C-elegans
Siler H. Panowski et al.
NATURE (2007)
Common aging pathways in worms, flies, mice and humans
Stuart K. Kim
JOURNAL OF EXPERIMENTAL BIOLOGY (2007)
Accelerated notch-dependent degradation of E47 proteins in aged B cell precursors is associated with increased ERK MAPK activation
Anne M. King et al.
JOURNAL OF IMMUNOLOGY (2007)
Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase
Daoying Hu et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2007)
RLE-1, an E3 ubiquitin ligase, regulates C. Elegans aging by catalyzing DAF-16 polyubiquitination
Wensheng Li et al.
DEVELOPMENTAL CELL (2007)
Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan
DW Walker et al.
CURRENT BIOLOGY (2006)
Lipoprotein genotype and conserved pathway for exceptional longevity in humans
G Atzmon et al.
PLOS BIOLOGY (2006)
Opinion - Programmed and altruistic ageing
VD Longo et al.
NATURE REVIEWS GENETICS (2005)
Transcriptional feedback control of insulin receptor by dFOXO/FOXO1
O Puig et al.
GENES & DEVELOPMENT (2005)
Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila
ACV Bayne et al.
BIOCHEMICAL JOURNAL (2005)
Suppression of aging in mice by the hormone Klotho
H Kurosu et al.
SCIENCE (2005)
p63 deficiency activates a program of cellular senescence and leads to accelerated aging
WM Keyes et al.
GENES & DEVELOPMENT (2005)
Epigenetic differences arise during the lifetime of monozygotic twins
MF Fraga et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression
J Halaschek-Wiener et al.
GENOME RESEARCH (2005)
JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
SW Oh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Sex and death: What is the connection?
L Partridge et al.
CELL (2005)
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
SJ Broughton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span
M Hertweck et al.
DEVELOPMENTAL CELL (2004)
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones
JF Morley et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
PTH and phospholipase A2 in the aging process of intestinal cells
C Gentili et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
B Rogina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
DS Hwangbo et al.
NATURE (2004)
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
P Kapahi et al.
CURRENT BIOLOGY (2004)
Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts
MA Casillas et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
M Narita et al.
CELL (2003)
The age-related inverse relationship between ob and lipogenic enzymes genes expression in rat white adipose tissue
A Nogalska et al.
EXPERIMENTAL GERONTOLOGY (2003)
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
M Holzenberger et al.
NATURE (2003)
JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila
MC Wang et al.
DEVELOPMENTAL CELL (2003)
Epigenetic regulation of an IAP retrotransposon in the aging mouse: progressive demethylation and de-silencing of the element by its repetitive induction
W Barbot et al.
NUCLEIC ACIDS RESEARCH (2002)
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
DJ Clancy et al.
SCIENCE (2001)
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
M Tatar et al.
SCIENCE (2001)
Targeted neuronal gene expression and longevity in Drosophila
JP Phillips et al.
EXPERIMENTAL GERONTOLOGY (2000)
Genetic pathways that regulate ageing in model organisms
L Guarente et al.
NATURE (2000)
Accelerated methylation of ribosomal RNA genes during the cellular senescence of Werner syndrome fibroblasts
A Machwe et al.
FASEB JOURNAL (2000)