Related references
Note: Only part of the references are listed.Cancer statistics, 2013
Rebecca Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2013)
Targeting Mutant KRAS for Anticancer Therapeutics: A Review of Novel Small Molecule Modulators
Yuanxiang Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Prenylation: From bacteria to eukaryotes
E. S. Marakasova et al.
MOLECULAR BIOLOGY (2013)
CANCER Double-pronged approach to combat mutant KRAS
Alexandra Flemming
NATURE REVIEWS DRUG DISCOVERY (2013)
REGULATION OF SMALL GTPases BY GEFs, GAPs, AND GDIs
Jacqueline Cherfils et al.
PHYSIOLOGICAL REVIEWS (2013)
In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction
Fumi Shima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
'Pathway drug cocktail': targeting Ras signaling based on structural pathways
Ruth Nussinov et al.
TRENDS IN MOLECULAR MEDICINE (2013)
Mutant and Wild-type Ras: Co-conspirators in Cancer
Tikvah K. Hayes et al.
CANCER DISCOVERY (2013)
The role of Rac1 in the regulation of NFκB activity, cell proliferation and cell migration in non-small cell lung carcinoma
Adam J. Gastonguay et al.
CANCER BIOLOGY & THERAPY (2012)
Inhibition of Tumor Promotion by Parthenolide: Epigenetic Modulation of p21
Akram Ghantous et al.
CANCER PREVENTION RESEARCH (2012)
Ras/ERK1 pathway regulation of p27KIP1-mediated G1-phase cell-cycle arrest in cordycepin-induced inhibition of the proliferation of vascular smooth muscle cells
Su-Mi Jung et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Thrombin induces MCP-1 expression through Rho-kinase and subsequent p38MAPK/NF-κB signaling pathway activation in vascular endothelial cells
Daiji Kawanami et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
SmgGDS Is a Guanine Nucleotide Exchange Factor That Specifically Activates RhoA and RhoC
Brant Hamel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Protein and its Function Based on a Subcellular Localization
Jana Cmielova et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2011)
Targeting protein prenylation for cancer therapy
Norbert Berndt et al.
NATURE REVIEWS CANCER (2011)
PIK3CA Mutation Uncouples Tumor Growth and Cyclin D1 Regulation from MEK/ERK and Mutant KRAS Signaling
Ensar Halilovic et al.
CANCER RESEARCH (2010)
Ubiquitylation and proteasomal degradation of the p21Cip1, p27Kip1 and p57Kip2 CDK inhibitors
Zhimin Lu et al.
CELL CYCLE (2010)
Splice Variants of SmgGDS Control Small GTPase Prenylation and Membrane Localization
Tracy J. Berg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The Cyclin-Dependent Kinase Inhibitor p21 Is a Crucial Target for Histone Deacetylase 1 as a Regulator of Cellular Proliferation
Gordin Zupkovitz et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Rac1 GTPase: A Rac of All Trades
E. E. Bosco et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
SmgGDS is up-regulated in prostate carcinoma and promotes tumour phenotypes in prostate cancer cells
H. Zhi et al.
JOURNAL OF PATHOLOGY (2009)
Suppression of Cancer Cell Growth by Promoting Cyclin D1 Degradation
Jing Shan et al.
MOLECULAR CELL (2009)
Abnormal expression of p120-catenin, E-cadherin, and small GTPases is significantly associated with malignant phenotype of human lung cancer
Yang Liu et al.
LUNG CANCER (2009)
Cell cycle, CDKs and cancer: a changing paradigm
Marcos Malumbres et al.
NATURE REVIEWS CANCER (2009)
Role of Rho GTPases in breast cancer
Yong Tang et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
Ral GTPases and cancer: linchpin support of the tumorigenic platform
Brian O. Bodemann et al.
NATURE REVIEWS CANCER (2008)
SmgGDS regulates cell proliferation, migration, and NF-κB transcriptional activity in non-small cell lung carcinoma
Gaik Wei Tew et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Regulation of the p27Kip1 tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
Carlos le Sage et al.
EMBO JOURNAL (2007)
Molecular prognostic markers in pancreatic cancer: A systematic review
G Garcea et al.
EUROPEAN JOURNAL OF CANCER (2005)
Opinion - Post-prenylation-processing enzymes as new targets in oncogenesis
AM Winter-Vann et al.
NATURE REVIEWS CANCER (2005)
RAS and RHO GTPases in G1-phase cell-cycle regulation
ML Coleman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1
CC Lanning et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences
CL Williams
CELLULAR SIGNALLING (2003)
Activation of Akt/protein kinase B overcomes a G2/M cell cycle checkpoint induced by DNA damage
ES Kandel et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Timing of cyclin D1 expression within G1 phase is controlled by Rho
CF Welsh et al.
NATURE CELL BIOLOGY (2001)
Blocking oncogenic Ras signaling for cancer therapy
AA Adjei
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
Rho GTPases are involved in the regulation of NF-κB by genotoxic stress
R Gnad et al.
EXPERIMENTAL CELL RESEARCH (2001)
Share Paper
