Journal
JOURNAL OF BIOLOGICAL PHYSICS
Volume 29, Issue 2-3, Pages 257-261Publisher
KLUWER ACADEMIC PUBL
DOI: 10.1023/A:1024409329416
Keywords
cancer; epithelial; frequency domain; skin; terahertz imaging; time domain spectroscopy
Categories
Ask authors/readers for more resources
Terahertz Pulsed Imaging (TPI) is a new medical imaging modality for the detection of epithelial cancers. Over the last two years this technique has been applied to the study of in vitro basal cell carcinoma (BCC). Using time-domain analysis the contrast between diseased and normal tissue has been shown to be statistically significant, and regions of increased terahertz (THz) absorption correlated well with the location of the tumour sites in histology. Understanding the source of this contrast through frequency-domain analysis may facilitate the diagnosis of skin cancer and related skin conditions using TPI. We present the first frequency-domain analysis of basal cell carcinoma in vitro, with the raw power spectrum giving an insight into the surface features of the skin. Further data manipulation is required to determine whether spectral information can be extrapolated at depth. These results highlight the complexity of working in reflection geometry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available