Related references
Note: Only part of the references are listed.SUMO and ubiquitin paths converge
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Rac and Rho GTPases in cancer cell motility control
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Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells
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TLR2-Induced Calpain Cleavage of Epithelial Junctional Proteins Facilitates Leukocyte Transmigration
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Tiam1 and Rac1 Are Required for Platelet-activating Factor-induced Endothelial Junctional Disassembly and Increase in Vascular Permeability
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Nuclear Cyclin D1: An Oncogenic Driver in Human Cancer
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JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Src-Induced Disassembly of Adherens Junctions Requires Localized Phosphorylation and Degradation of the Rac Activator Tiam1
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Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis
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Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement
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CELL (2008)
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GENES TO CELLS (2008)
Joint Requirement for Rac and ERK Activities Underlies the Mid-G1 Phase Induction of Cyclin D1 and S Phase Entry in Both Epithelial and Mesenchymal Cells
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Rho family GTPase modification and dependence on CAAX motif-signaled posttranslational modification
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JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division
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PAK is required for the disruption of E-cadherin adhesion by the small GTPase Rac
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JOURNAL OF CELL SCIENCE (2008)
Increased Rac1b expression sustains colorectal tumor cell survival
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MOLECULAR CANCER RESEARCH (2008)
Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis
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LEUKEMIA (2008)
Rac guanosine triphosphatases represent a potential target in AML
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LEUKEMIA (2008)
Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis
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SCIENCE (2008)
Nonadherent cells switch to a Rac-mediated, SHIP regulated, Akt activation mode for survival
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ONCOGENE (2008)
Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process
Orane Visvikis et al.
FEBS JOURNAL (2008)
Cytokinesis: Placing and making the final cut
Francis A. Barr et al.
CELL (2007)
Cutting edge: Rac GTPases sensitize activated T Cells to die via Fas
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JOURNAL OF IMMUNOLOGY (2007)
Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease
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CANCER CELL (2007)
α6β4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-κB-dependent resistance to apoptosis in 3D mammary acini
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Requirement for Rac1 in a K-ras-induced lung cancer in the mouse
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CANCER RESEARCH (2007)
What tangled webs they weave: Rho-GTPase control of angiogenesis
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CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Sndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix
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JOURNAL OF CELL BIOLOGY (2007)
The spindle-assembly checkpoint in space and time
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
NFκB-independent signaling to the cyclin D1 gene by Rac
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C-terminal Src kinase controls development and maintenance of mouse squamous epithelia
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Rac activity is polarized and regulates meiotic spindle stability and anchoring in mammalian oocytes
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Rac1 GTPase regulates cell genomic stability and senescence
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells
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MOLECULAR BIOLOGY OF THE CELL (2006)
Mechanisms of chromosome instability in cancers
Charles Edward Jefford et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2006)
Proteasome-mediated degradation of Rac1-GTP during epithelial cell scattering
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MOLECULAR BIOLOGY OF THE CELL (2006)
Rho GTPases in animal cell mitosis
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CURRENT OPINION IN CELL BIOLOGY (2006)
Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA
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MOLECULAR AND CELLULAR BIOLOGY (2006)
The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex
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JOURNAL OF CELL BIOLOGY (2005)
Expression of Rac1b stimulates NF-κB-mediated cell survival and G1/S progression
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EXPERIMENTAL CELL RESEARCH (2005)
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ADVANCED DRUG DELIVERY REVIEWS (2005)
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1
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NATURE CELL BIOLOGY (2005)
Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
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JOURNAL OF CELL SCIENCE (2004)
Expression of seven main Rho family members in gastric carcinoma
YL Pan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
A novel role of nectins in inhibition of the e-cadherin-induced activation of Rac and formation of cell-cell adherens junctions
T Hoshino et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Isotype-specific degradation of Rac activated by the cytotoxic necrotizing factor 1
M Pop et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin
M Bruewer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions
A Malliri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer
T Kamai et al.
CLINICAL CANCER RESEARCH (2004)
Mutations in sticky lead to defective organization of the contractile ring during cytokinesis and are enhanced by Rho and suppressed by Rac
PP D'Avino et al.
JOURNAL OF CELL BIOLOGY (2004)
Overexpression of Rac-1 small GTPase binding protein in oral squamous cell carcinoma
SY Liu et al.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY (2004)
Cell type-specific regulation of RhoA activity during cytokinesis
H Yoshizaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cleavage of β-catenin by calpain in prostate and mammary tumor cells
J Rios-Doria et al.
CANCER RESEARCH (2004)
The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1
CC Lanning et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Differential interaction and activation of Rho family GTPases by p210bcr-abl and p190bcr-abl
T Harnois et al.
ONCOGENE (2003)
Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: Analysis with the N-cadherin dominant negative mutant
Y Tanaka et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density
MS Balda et al.
JOURNAL OF CELL BIOLOGY (2003)
The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells
J Rios-Doria et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A RhoGEF and Rho family GTPase-activating protein complex links the contractile ring to cortical microtubles at the onset of cytokinesis
WG Somers et al.
DEVELOPMENTAL CELL (2003)
trans-interactions of nectins induce formation of filopodia and lamellipodia through the respective activation of Cdc42 and Rac small G proteins
T Kawakatsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion
JS Ehrlich et al.
DEVELOPMENTAL CELL (2002)
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours
A Malliri et al.
NATURE (2002)
E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts
EM Kovacs et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity
M Mishima et al.
DEVELOPMENTAL CELL (2002)
Timing of cyclin D1 expression within G1 phase is controlled by Rho
CF Welsh et al.
NATURE CELL BIOLOGY (2001)
Cadherin engagement regulates Rho family GTPases
NK Noren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly
LE O'Brien et al.
NATURE CELL BIOLOGY (2001)
Integrin-specific activation of Rac controls progression through the G1 phase of the cell cycle
A Mettouchi et al.
MOLECULAR CELL (2001)
RAC1 regulates adherens junctions through endocytosis of E-cadherin
N Akhtar et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes
VMM Braga et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Localized Rac activation dynamics visualized in living cells
VS Kraynov et al.
SCIENCE (2000)
Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b
A Schnelzer et al.
ONCOGENE (2000)
The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression
MS Balda et al.
EMBO JOURNAL (2000)
Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway
JP Mira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)