Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 18, Issue 11, Pages 2002-2009Publisher
WILEY
DOI: 10.1359/jbmr.2003.18.11.2002
Keywords
osteoclast; bone formation rate; cortical bone; alkaline phosphatase; mineralized nodule; exercise bone
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To investigate the relationship between the effects of bone turnover and bone marrow cell development in bone cells, we developed a mouse voluntary climbing exercise model. Climbing exercise increased bone volume and transient osteogenic potential of bone marrow. This model would be suitable for investigating the mechanistic roles of mechanical loading.
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