Journal
NUCLEIC ACIDS RESEARCH
Volume 31, Issue 1, Pages 474-477Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkg086
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Funding
- NATIONAL LIBRARY OF MEDICINE [ZIALM000046, Z01LM000046, Z01LM000057] Funding Source: NIH RePORTER
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dimensional structures are now known within most protein families and it is likely, when searching a sequence database, that one will identify a homolog of known structure. The goal of Entrez' s 3D- structure database is to make structure information and the functional annotation it can provide easily accessible to molecular biologists. To this end, Entrez' s search engine provides several powerful features: ( i) links between databases, for example between a protein s sequence and structure; ( ii) precomputed sequence and structure neighbors; and ( iii) structure and sequence/ structure alignment visualization. Here, we focus on a new feature of Entrez' s Molecular Modeling Database ( MMDB) : Graphical summaries of the biological annotation available for each 3D structure, based on the results of automated comparative analysis. MMDB is available at: http: / / www. ncbi. nlm. nih. gov/ Entrez/ structure. html.
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