4.7 Article

Synthesis of a novel C2-aryl substituted 1,2-unsaturated pyrrolobenzodiazepine

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 14, Pages 1688-1689

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b303274d

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A novel C2-aryl 1,2-unsaturated PBD (14) has been prepared via an enol triflate intermediate (8). The regiochemistry of triflation is dependent upon the point at which the reaction is performed during the synthetic route.

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