Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 2, Pages 196-197Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b209892j
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Funding
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL064731] Funding Source: NIH RePORTER
- NHLBI NIH HHS [HL64731] Funding Source: Medline
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We report studies toward the total synthesis of an epoxy isoprostane, namely the preparation of compound 9 which is an analogue of the elimination product 7 of the naturally occurring epoxy isoprostane 4 by a straightforward route using a three-component coupling, and have shown by several spectroscopic criteria that it closely resembles the natural material.
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