Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 23, Pages 2870-2871Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b309196a
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We have successfully synthesized a number of small molecule probes designed for site- specific labeling of N-terminal cysteine- containing proteins expressed in live cells. Their utility for site- specific, covalent modifications of proteins was successfully demonstrated with purified proteins in vitro, and with live bacterial cells in vivo.
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