Journal
MOLECULAR BIOLOGY OF THE CELL
Volume 14, Issue 12, Pages 4805-4812Publisher
AMER SOC CELL BIOLOGY
DOI: 10.1091/mbc.E03-06-0395
Keywords
-
Categories
Funding
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM060551, R01GM021595] Funding Source: NIH RePORTER
- NIGMS NIH HHS [R01 GM060551, GM-21595, GM-60551] Funding Source: Medline
Ask authors/readers for more resources
Although the complex process of ribosome assembly in the nucleolus is beginning to be understood, little is known about how the ribosomal subunits move from the nucleolus to the nuclear membrane for transport to the cytoplasm. We show here that large ribosomal subunits move out from the nucleolus and into the nucleoplasm in all directions, with no evidence of concentrated movement along directed paths. Mobility was slowed compared with that expected in aqueous solution in a manner consistent with anomalous diffusion. Once nucleoplasmic, the subunits moved in the same random manner and also sometimes visited another nucleolus before leaving the nucleus.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available