Journal
MAGNETIC RESONANCE IN MEDICINE
Volume 49, Issue 1, Pages 151-157Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/mrm.10337
Keywords
magnetic resonance imaging (MRI); fast imaging; steady-state free precession (SSFP); MR angiography; coronary arteries; image artifacts
Funding
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL038698] Funding Source: NIH RePORTER
- NHLBI NIH HHS [HL38698] Funding Source: Medline
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An electrocardiogram (ECG)-triggered, magnetization-pre- pared, segmented, 3D true fast imaging with steady-state precession (true-FISP) sequence with fat saturation was recently proposed for coronary artery imaging. A magnetization preparation scheme consisting of an alpha/2 radiofrequency (RF) pulse followed by 20 constant flip angle dummy RF cycles was used to reduce signal oscillations in the approach to steady state. However, if large resonance offsets on the order of 70-100 Hz are present, significant magnetization oscillations will still occur during data acquisition, which will result in image ghosting and blurring. The goal of this work was to validate that a linear flip angle (LFA) series can be used during magnetization preparation to reduce these image artifacts. Computer simulations, phantom studies, and coronary artery imaging in healthy volunteers were performed to compare this magnetization preparation scheme with that of an alpha/2 pulse followed by constant flip angle dummy RF cycles. The results demonstrated substantial reduction in the apparent image artifacts when using linearly increasing flip angles during magnetization preparation. (C) 2003 Wiley-Liss, Inc.
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