4.1 Article Proceedings Paper

Conjugates of oligo(2 '-O-methylribonucleotides) with minor groove binders as new sequence-specific agents recognizing both grooves of double-stranded DNA

Journal

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Volume 22, Issue 5-8, Pages 1179-1182

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1081/NCN-120022830

Keywords

oligo (Z '-methylribonucleotides); conjugates; minor groove binders; triplex formation

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Design, synthesis and physico-chemical studies of new pyrimidine oligo(2'-O-methylribonucleotide) conjugates with one or two oligo(pyrrolecarboxamide) minor groove binders (MGB) are described.

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