Journal
CELL
Volume 159, Issue 3, Pages 487-498Publisher
CELL PRESS
DOI: 10.1016/j.cell.2014.09.054
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Funding
- United States Public Health Service [RO1-GM34277, R01-CA133404, U54-CA112967]
- National Cancer Institute [P30-CA14051]
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Coherent splicing networks arise from many discrete splicing decisions regulated in unison. Here, we examine the properties of robust, context-specific splicing networks. We propose that a subset of key splicing regulators, or master splicing factors, respond to environmental cues to establish and maintain tissue transcriptomes during development.
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