Journal
CELL
Volume 158, Issue 5, Pages 980-987Publisher
CELL PRESS
DOI: 10.1016/j.cell.2014.08.005
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Funding
- Institute for Basic Science (IBS) from the Ministry of Science, Information, and Communication Technology (ICT) [EM1402]
- Future Planning of Korea
- BK21 Research Fellowships from the Ministry of Education of Korea
- Ministry of Science, ICT & Future Planning, Republic of Korea [IBS-R008-D1-2014-A00] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Although more than 100 types of RNA modification have been described thus far, most of them were thought to be rare in mRNAs and in regulatory noncoding RNAs. Recent developments have unveiled that at least some of the modifications are considerably abundant and widely conserved. This Minireview summarizes the molecular machineries and biological functions of methylation (N6-methyladenosine, m(6)A) and uridylation (U-tail).
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