Journal
CELL
Volume 154, Issue 6, Pages 1194-1205Publisher
CELL PRESS
DOI: 10.1016/j.cell.2013.08.053
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Funding
- Cancer Research, UK
- Cancer Research UK [11244] Funding Source: researchfish
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An adult animal consists of cells of vastly different size and activity, but the regulation of cell size remains poorly understood. Recent studies uncovering some of the signaling pathways important for size/growth control, together with the identification of diseases resulting from aberrations in these pathways, have renewed interest in this field. This Review will discuss our current understanding of how a cell sets its size, how it can adapt its size to a changing environment, and how these processes are relevant to human disease.
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