Journal
CELL
Volume 153, Issue 3, Pages 516-519Publisher
CELL PRESS
DOI: 10.1016/j.cell.2013.04.003
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Funding
- Cancer Research UK
- Oxford Division of Structural Biology is part of the Wellcome Trust Centre for Human Genetics, Wellcome Trust Core Award [090532/Z/09/Z]
- Cancer Research UK [13070] Funding Source: researchfish
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MicroRNAs (miRNAs) are versatile regulators of gene expression in higher eukaryotes. In order to silence many different mRNAs in a precise manner, miRNA stability and efficacy is controlled by highly developed regulatory pathways and fine-tuning mechanisms both affecting miRNA processing and altering mature miRNA target specificity.
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