Journal
CELL
Volume 155, Issue 5, Pages 990-996Publisher
CELL PRESS
DOI: 10.1016/j.cell.2013.10.048
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Funding
- United States Public Health Service grants from the National Institutes of Health [RO1-GM34277, R01-CA133404]
- Koch Institute Support from the National Cancer Institute [P30-CA14051]
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The mammalian genome is extensively transcribed, a large fraction of which is divergent transcription from promoters and enhancers that is tightly coupled with active gene transcription. Here, we propose that divergent transcription may shape the evolution of the genome by new gene origination.
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