Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 4, Issue 12, Pages 960-970Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm1259
Keywords
-
Categories
Ask authors/readers for more resources
Almost 20 years after the discovery of introns and RNA splicing, a second spliceosome was uncovered. Although this new spliceosome is structurally and functionally analogous to the well-characterized major-class splicing apparatus, it mediates the excision of a minor class of evolutionarily conserved introns that have non-canonical consensus sequences. This unanticipated diversity in the splicing machinery is refining both the mechanistic understanding and evolutionary models of RNA splicing.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available