Journal
CELL
Volume 151, Issue 1, Pages 11-13Publisher
CELL PRESS
DOI: 10.1016/j.cell.2012.09.006
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Funding
- Cancer Research UK [12077, 13061] Funding Source: researchfish
- Cancer Research UK [12077, 13061] Funding Source: Medline
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Myc is an enigma wrapped in a mystery. Attempts to identify Myc target genes, particularly in cancer, have been fraught with dead ends and context-specific functions. Lin et al. and Nie et al. address this conundrum by showing that Myc acts to amplify the output of existing transcriptionally active genes.
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