Journal
CELL
Volume 148, Issue 6, Pages 1081-1084Publisher
CELL PRESS
DOI: 10.1016/j.cell.2012.02.034
Keywords
-
Categories
Funding
- National Cancer Institute [CA51008, CA50633, T32-CA009686]
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By targeting surface antigens expressed on tumor cells, monoclonal antibodies have demonstrated efficacy as cancer therapeutics. Recent successful antibody-based strategies have focused on enhancing antitumor immune responses by targeting immune cells, irrespective of tumor antigens. We discuss these innovative strategies and propose how they will impact the future of antibody-based cancer therapy.
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