Journal
CELL
Volume 148, Issue 1-2, Pages 29-32Publisher
CELL PRESS
DOI: 10.1016/j.cell.2012.01.006
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Funding
- NIH [R00CA149182-03]
- Prostate Cancer Foundation
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The unprecedented resolution of high-throughput genomics has enabled the recent discovery of a phenomenon by which specific regions of the genome are shattered and then stitched together via a single devastating event, referred to as chromothripsis. Potential mechanisms governing this process are now emerging, with implications for our understanding of the role of genomic rearrangements in development and disease.
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