Journal
CELL
Volume 149, Issue 1, Pages 11-12Publisher
CELL PRESS
DOI: 10.1016/j.cell.2012.03.011
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Funding
- NIGMS NIH HHS [R01 GM058673] Funding Source: Medline
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Meiotic cells tightly regulate the number and distribution of crossovers to promote accurate chromosome segregation. Yokoo and colleagues uncover a metazoan-specific, cyclin-like protein that is crucial for crossover formation. They utilize this protein's unique properties to explore a remarkable example of biological numerology, whereby nearly every meiotic cell in C. elegans makes precisely six crossovers, one for each of its six chromosome pairs.
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