Journal
CELL
Volume 149, Issue 5, Pages 961-963Publisher
CELL PRESS
DOI: 10.1016/j.cell.2012.05.004
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LINC complexes are structures embedded within the nuclear envelope that mechanically couple the nucleus and cytoskeleton. They consist of SUN domain proteins of the inner nuclear membrane associated with KASH domain proteins in the outer nuclear membrane. Atomic resolution structures of SUN-KASH pairs now provide new insight in to the mechanisms of LINC complex assembly.
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