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The Human Brain in a Dish: The Promise of iPSC-Derived Neurons

Journal

CELL
Volume 145, Issue 6, Pages 831-834

Publisher

CELL PRESS
DOI: 10.1016/j.cell.2011.05.034

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Funding

  1. NIH
  2. NIA
  3. NIGMS
  4. Autism Speaks
  5. Simons Foundation

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Induced pluripotent stem cell-derived neurons from patients promise to fill an important niche between studies in humans and model organisms in deciphering mechanisms and identifying therapeutic avenues for neurologic and psychiatric diseases. Recent work begins to tap this potential and also highlights challenges that must be overcome to be fully realized.

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