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RIP Kinases at the Crossroads of Cell Death and Survival

Journal

CELL
Volume 138, Issue 2, Pages 229-232

Publisher

CELL PRESS
DOI: 10.1016/j.cell.2009.07.006

Keywords

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Funding

  1. VIB
  2. UGhent
  3. FP6 ApopTrain [MRTN-CT-035624]
  4. FP6 Epistem [LSHB-CT-2005-019067]
  5. Apo-Sys [FP7-200767, IAP 6/18]
  6. FWO-Vlaanderen [3G.0218.06, G.0226.09]
  7. [BOF-GOA-12.0505.02]

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Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor proteins to regulate cell death. Recent studies (Cho et al., 2009; He et al., 2009; Zhang et al., 2009) reveal that the RIP3 kinase functions with RIP1 at the crossroads of apoptosis, necroptosis, and cell survival.

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