Journal
CELL
Volume 137, Issue 1, Pages 26-28Publisher
CELL PRESS
DOI: 10.1016/j.cell.2009.03.024
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Funding
- Howard Hughes Medical Institute Funding Source: Medline
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Mutations in the gene encoding the orphan nuclear receptor Nurr1 are linked to a rare familial form of Parkinson's disease. By examining the function of its mouse homolog, Saijo et al. (2009) provide evidence that Nurr1 protects dopaminergic neurons by suppressing inflammatory gene expression in astrocytes and microglia.
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