Journal
EXPERIMENTAL GERONTOLOGY
Volume 38, Issue 11-12, Pages 1329-1332Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.exger.2003.10.020
Keywords
RNAi; mutations; genetics of aging; longevity; Daf-16
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The nematode Caenorhabditis elegans has been the organism of choice for most aging research, especially genetic appraoches to aging. More than 70 longevity genes have been identified, with more to come, and these genes have been the subjects of intense study. I identify the major reasons for this and discuss limitations of this organism for future progress in research on aging. (C) 2003 Elsevier Inc. All rights reserved.
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