Journal
CELL
Volume 136, Issue 2, Pages 207-208Publisher
CELL PRESS
DOI: 10.1016/j.cell.2009.01.003
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Funding
- NIGMS NIH HHS [R01 GM079431-04, R01 GM059136, R01 GM059136-09, GM079431, R01 GM079431, GM059136, R56 GM059136] Funding Source: Medline
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Cellular determinants of the germline selectively accumulate in germ cell precursors and influence cell fate during early development in many organisms. Zhang et al. (2009) now report that targeted autophagy mediated by the SEPA-1 protein depletes germplasm proteins from somatic cells during early development of the nematode.
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