Journal
CELL
Volume 132, Issue 2, Pages 185-195Publisher
CELL PRESS
DOI: 10.1016/j.cell.2008.01.003
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Funding
- NICHD NIH HHS [R37 HD021502, R01 HD021502-21A1, R01 HD021502, HD21502-21] Funding Source: Medline
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Most animals evolved from a common ancestor, Urbilateria, which already had in place the developmental genetic networks for shaping body plans. Comparative genomics has revealed rather unexpectedly that many of the genes present in bilaterian animal ancestors were lost by individual phyla during evolution. Reconstruction of the archetypal developmental genomic tool-kit present in Urbilateria will help to elucidate the contribution of gene loss and developmental constraints to the evolution of animal body plans.
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