Journal
CELL
Volume 135, Issue 6, Pages 1013-1016Publisher
CELL PRESS
DOI: 10.1016/j.cell.2008.11.026
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Funding
- NIA NIH HHS [R01 AG024379] Funding Source: Medline
- NIEHS NIH HHS [P01 ES014635] Funding Source: Medline
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Mammalian aging results from a replicative decline in the function of somatic stem cells and other self-renewing cells. Recent studies (Monzen et al., 2008; Nishino et al., 2008; Sanna et al., 2008; Weedon et al., 2008) link a chromatin-associated protein, HMGA2, to development, height, and mouse stem cell aging during late fetal development and young adulthood.
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