Journal
CELL
Volume 133, Issue 6, Pages 958-961Publisher
CELL PRESS
DOI: 10.1016/j.cell.2008.05.027
Keywords
-
Categories
Funding
- NIA NIH HHS [R01 AG023145-05, R01 AG023145] Funding Source: Medline
Ask authors/readers for more resources
Although initially described as the end state of cells after extended rounds of division in culture, it is now clear that cellular senescence induced by different stimuli plays an important role in tumor suppression in vivo. Three recent studies in Cell report that secreted proteins play an important role in enforcing the senescence response (Acosta et al., 2008; Kuilman et al., 2008; Wajapeyee et al., 2008). These new studies identify unanticipated contributors to this tumor-suppressing cell state.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available