Journal
CELL
Volume 135, Issue 3, Pages 417-420Publisher
CELL PRESS
DOI: 10.1016/j.cell.2008.10.007
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Funding
- PHS [R37 CA 30488]
- National Cancer Institute
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Three recent screens use siRNAs to identify host genes that are critical for HIV-1 replication. These screens have uncovered hundreds of human genes not previously known to be commandeered by the virus during infection. Although some caveats remain, this screening approach opens up a new landscape of viral-host interactions for future exploration.
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