Journal
CELL
Volume 133, Issue 7, Pages 1133-1135Publisher
CELL PRESS
DOI: 10.1016/j.cell.2008.06.008
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Funding
- NIGMS NIH HHS [R01 GM054510] Funding Source: Medline
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Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.
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