Journal
NEURORADIOLOGY
Volume 45, Issue 1, Pages 34-38Publisher
SPRINGER
DOI: 10.1007/s00234-002-0891-y
Keywords
head injury; diffuse axonal injury; diffusion-weighted imaging
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Myelinated axons of white matter demonstrate prominent directional differences in water diffusion. We performed diffusion-weighted imaging on ten patients with head injury to explore the feasibility of using water diffusion anisotropy for quantitating diffuse axonal injury. We showed significant decrease in diffusion anisotropy indices in areas with or without signal abnormality on T2 and T2*-weighted images. We conclude that the water diffusion anisotropy sensitive index a potentially useful, and quantitative way of diagnosing and assessing patients with diffuse axonal injury.
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