Journal
BIOFACTORS
Volume 21, Issue 1-4, Pages 167-170Publisher
IOS PRESS
DOI: 10.1002/biof.552210134
Keywords
turmeric; ar-turmerone; curcumin; galactosamine; alanine aminotransferase; aspartate aminotransferase
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Hepatoprotective effect of turmeric together with its sesquiterpenes and curcuminoids fractions were examined on D-galactosamine induced liver injury in rats. All the diets individually contained the turmeric extract, the curcuminoids fraction, and the sesquiterpenes fraction suppressed the increase of LDH, ALT, and AST levels caused by D-GalN treatment. Since few anti-oxidative activities are expected in the sesquiterpenes fraction, it is presumed that hepatoprotective mechanism of sesquiterpenes in turmeric is different from that of curuminoids.
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