Journal
UROLOGIA INTERNATIONALIS
Volume 72, Issue 3, Pages 233-236Publisher
KARGER
DOI: 10.1159/000077122
Keywords
urolithiasis; zinc, urinary; copper, urinary; inhibitory effect of zinc
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Introduction: It is considered that many factors may play a role in urolithiasis. Experimental and clinical studies have shown that zinc has an inhibitory effect on urolithiasis. Materials and Methods: In this study, urinary zinc and copper were measured in 27 healthy controls and 30 calcium oxalate stone formers. Results: Urinary zinc excretion was significantly higher (p < 0.001) in stone formers than healthy controls ( 2,575 B 274 and 960 +/- 80 mg/day, respectively). There was no significant difference in urinary copper excretion between healthy controls and stone formers (32.3 +/- 3.5 and 33.3 +/- 3.2 mug/day, respectively). Conclusions: According to our results, the potent inhibitory effect of urinary zinc excretion on urolithiasis could be reviewed. Copyright (C) 2004 S. Karger AG, Basel.
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