Journal
FITOTERAPIA
Volume 75, Issue 1, Pages 24-31Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2003.07.008
Keywords
Spirulina fusiformis; cisplatin; urethane; genotoxicity
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Spirulina fusiformis given by oral route to mice at doses of 250, 500 and 1000 mg kg(-1) significantly inhibit the genotoxicity induced by cisplatin and urethane. In addition, a significant reduction in the extent of lipid peroxidation with concomitant increase in the liver enzymatic (GPx, GST, SOD, CAT) and non-enzymatic (reduced glutathione) antioxidants were observed. (C) 2003 Elsevier B.V. All rights reserved.
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