Journal
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
Volume 28, Issue 1, Pages 63-67Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00004728-200401000-00010
Keywords
bold oxygen level dependent (BOLD); functional magnetic resonance imaging (fMRI); object recognition; ventral occipito-temporal cortex (VOTC); word recognition
Funding
- NATIONAL EYE INSTITUTE [R01EY013801] Funding Source: NIH RePORTER
- NEI NIH HHS [R01 EY 13801] Funding Source: Medline
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We present a case of a 64-year-old, right-handed female with a metastatic breast cancer lesion involving the left posterior inferior temporal lobe causing complete loss of the ability to recognize visually common objects and words. After her symptoms resolved on corticosteroid therapy, functional magnetic resonance imaging (fMRI) mapping demonstrated strong left-hemispheric dominance for word recognition and right-hemispheric dominance for object recognition. The case illustrates the relationships among ventral occipito-temporal cortical activation, lesion localization, and lesioninduced deficits of higher visual function. The relationship between hemispheric dominance determined by fMRI and risk of postoperative deficit depends on the specific visual function of interest.
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