Journal
GREEN CHEMISTRY
Volume 6, Issue 3, Pages 147-150Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b314015f
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3,4-Dihydropyrimidin-2-(1H)-ones have been synthesized in excellent yields in short reaction time at ambient temperature in the absence of any added catalyst by the reaction of aromatic or aliphatic aldehydes with ethyl acetoacetate (EAA) and urea (or thiourea) in room temperature ionic liquid (IL) under ultrasound irradiation. The evidence for the role of IL in promoting this multicomponent reaction has been given. Based on this evidence, a plausible mechanistic pathway has been postulated.
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