Journal
CURRENT OPINION IN GASTROENTEROLOGY
Volume 20, Issue 1, Pages 43-48Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001574-200401000-00009
Keywords
colorectal carcinoma; Crohn disease; ulcerative colitis; inflammatory bowel disease; colon cancer
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Purpose of review Patients with inflammatory bowel disease, either Crohn disease or ulcerative colitis, are at an increased risk for developing colorectal carcinoma. Recent findings Surveillance colonoscopy, although never formally evaluated in a prospective controlled trial, is performed in an effort to reduce this risk. Novel methods of detecting dysplasia are constantly being evaluated, including chromoendoscopy and biomarkers of carcinoma, in an attempt to stratify patients who are at a higher risk of developing high-grade dysplasia or carcinoma. Summary Because of the potential impact on quality of life and life expectancy, an optimal strategy for reducing the risk of developing colorectal cancer in patients with inflammatory bowel disease needs to be defined.
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