Journal
BIOLOGY OF THE NEONATE
Volume 85, Issue 4, Pages 293-298Publisher
KARGER
DOI: 10.1159/000078174
Keywords
severe acute respiratory syndrome; coronavirus
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The severe acute respiratory syndrome (SARS) is a highly contagious infection caused by a newly discovered strain of coronavirus (SARS-CoV). Infants born to pregnant women with SARS did not appear to acquire the infection through vertical transmission. Some newborn infants, however, developed severe intrauterine growth retardation and life-threatening gastrointestinal complications. It is now known that the clinical course and prognosis are different between paediatric and adult SARS patients. Young children (<12 years), in general, run a less aggressive clinical course than do teenage and adult patients. Thus far, no fatalities have been reported in the paediatric age group (<= 18 years). This review describes the current understanding of the clinical manifestations, diagnostic tests, immunological profiles, patient management and outcomes of SARS-CoV infection in the paediatric population. Copyright (C) 2004 S. Karger AG, Basel.
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