Journal
JOURNAL OF VISION
Volume 4, Issue 4, Pages 250-261Publisher
ASSOC RESEARCH VISION OPHTHALMOLOGY INC
DOI: 10.1167/4.4.1
Keywords
aberrations; lens; accommodation
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Funding
- NEI NIH HHS [R01 EY014651-01, R01 EY014651, R01 EY 014651-01] Funding Source: Medline
- NATIONAL EYE INSTITUTE [R01EY014651] Funding Source: NIH RePORTER
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A method to measure wave aberrations in the isolated crystalline lens is demonstrated. The method employs a laser scanning technique in which the trajectories of narrow refracted laser beams are measured for an array of sample positions incident on the lens. The local slope of the emerging wavefront is calculated for each sample position, and a least squares procedure is used to fit a Zernike polynomial function to define the wave aberration. Measurements of the aberrations of an isolated porcine lens and macaque lens undergoing changes in accommodative state with mechanical stretching are shown. Many aberrations were present, but negative spherical aberration dominated. In the macaque lens, many aberrations underwent systematic changes with accommodation, most notably the 4(th) order spherical aberration, which became more negative, and the 6(th) order spherical aberration, which progressed from negative to positive.
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